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Latest Publications

Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides

O. Sallin; L. Reymond; C. Gondrand; F. Raith; B. Koch et al.

eLife. 2018-05-29.

DOI : 10.7554/eLife.32638.

Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor (vol 8, 1862, 2017)

M. Berry; A. Holt; J. Levitz; J. Broichhagen; B. Gaub et al.

NATURE COMMUNICATIONS. 2018.

DOI : 10.1038/s41467-018-03585-2.

Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons

R. Dhandapani; C. Arokiaraj; F. Taberner; P. Pacifico; S. Raja et al.

NATURE COMMUNICATIONS. 2018.

DOI : 10.1038/s41467-018-04049-3.

A New Fluorogenic Small-Molecule Labeling Tool for Surface Diffusion Analysis and Advanced Fluorescence Imaging of beta-site Amyloid Precursor Protein-Cleaving Enzyme 1 Based on Silicone Rhodamine: SiR-BACE1

S. Karch; J. Broichhagen; J. Schneider; D. Boning; S. Hartmann et al.

JOURNAL OF MEDICINAL CHEMISTRY. 2018.

DOI : 10.1021/acs.jmedchem.8b00387.

Sampling and Energy Evaluation Challenges in Ligand Binding Protein Design

J. Dou; L. Doyle; P. J. Greisen; A. Schena; H. Park et al.

Protein Science. 2017.

DOI : 10.1002/pro.3317.

Computational design of environmental sensors for the potent opioid fentanyl

M. J. Bick; P. J. Greisen; K. J. Morey; M. S. Antunes; D. La et al.

eLife. 2017.

DOI : 10.7554/eLife.28909.

Luciferases with tunable emission wavelengths

K. Johnsson; J. Hiblot; Q. Yu; M. Sabbadini; L. Reymond et al.

Angewandte Chemie International Edition. 2017.

DOI : 10.1002/anie.201708277.

Potent Prearranged Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor

B. J. Jones; R. Scopelliti; A. Tomas; S. R. Bloom; D. J. Hodson et al.

Chemistryopen. 2017.

DOI : 10.1002/open.201700062.